Transgenerational Immune Priming

Dalan Animal Health

How insects pass immunity to their offspring
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Immune pathways and defence mechanisms in honey bees Apis mellifera

Insect Molecular Biology

Social insects are able to mount both group-level and individual defences against pathogens. Here we focus on individual defences, by presenting a genome-wide analysis of immunity in a social insect, the honey bee Apis mellifera...
Read more at Insect Molecular Biology

The maternal transfer of bacteria can mediate trans-generational immune priming in insects


Parents invest in their offspring by preparing them for defense against pathogens and parasites that only the parents have encountered, a phenomenon known as trans-generational immune priming. We investigated the underlying mechanism using the established lepidopteran model host Galleria mellonella...
Read more at Virulence

Transfer of Immunity from Mother to Offspring Is Mediated via Egg-Yolk Protein Vitellogenin

PLOS Pathogens

Insect immune systems can recognize specific pathogens and prime offspring immunity. High specificity of immune priming can be achieved when insect females transfer immune elicitors into developing oocytes....
Read more at PLOS Pathogens

The role of Vitellogenin in the transfer of immune elicitors from gut to hypopharyngeal glands in honey bees (Apis mellifera)

Journal of Insect Physiology

Female insects that survive a pathogen attack can produce more pathogen-resistant offspring in a process called trans-generational immune priming. In the honey bee (Apis mellifera), the egg-yolk precursor protein Vitellogenin transports fragments of pathogen cells into the egg, thereby setting the stage for a recruitment of immunological defenses prior to hatching....
Read more at the Journal of Insect Physiology